Lab tests: Obtain baseline and periodic determinations of serum potassium and other electrolytes.
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It works by slowing the action of certain enzymes that break food down into sugars.
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Adverse effects are listed in decreasing order of severity.
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WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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In addition, triamterene is a weak folic acid antagonist and can contribute to the development of megaloblastic anemia in patients with depleted stores of folic acid such as occur in hepatic cirrhosis.
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This monograph should not replace advice from a healthcare professional and should not be used for the diagnosis or treatment of any medical condition.
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Some products that may interact with this drug include: lithium, other drugs that may increase potassium levels (such as spironolactone, amiloride, cyclosporine).
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In some varieties this results in increases in androgenic hormones (which can cause virilization) and in deoxycorticosterone (which has mineralocorticoid activity and can cause hypertension).
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Medications should not be used after the expiration date printed on the container.
This diuresis leaves less water to be reabsorbed into the blood, resulting in a decrease in blood volume.
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An inverse relationship between dietary potassium intake at baseline and subsequent stroke-associated morbidity and mortality has also been noted in several, but not all, cross-sectional and cohort studies ().
The actions of some diuretics ( and in particular) are independent of their diuretic effect.
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Calling the patient by name is not as effective as having the patient state their name; patients may not hear well or understand what the nurse is saying, and may respond to a name which is not their own.
Because triamterene conserves potassium, it has been suggested that patients who have received intensive therapy or have been given the drug for prolonged periods may develop a rebound kaliuresis if such therapy is discontinued abruptly.
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Moreover, reducing the sodium intake by approximately 40 mmol per day caused a greater decrease in blood pressure when the starting sodium intake was already at the recommended level than when it was at a higher level similar to the average in the United States.
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Other serious side effects of triamterene-HCTZ may include kidney stones, stomach pain, severe nausea or vomiting, numbness or tingling in the limbs and unusual bleeding or bruising.
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Generally, thiazide diuretics are recommended for most patients with a diagnosis of hypertension; however, loop diuretics are more commonly prescribed for patients with decreased glomerular filtration rate or heart failure.
They should drink one glass with each meal and drink fluids at night, even if they have to get up during the night to go to the bathroom.
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This results in greater concentrations of these three in the brain.
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Triamterene and Hydrochlorothiazide Capsules, USP are also indicated for those patients who require a thiazide diuretic and in whom the development of hypokalemia cannot be risked.
La siguiente importante información de seguridad, sobre ésta medicina, es proporcionada por el programa Alerta Médica (MedWatch) de la Administración de Alimentos y Medicamentos (FDA).
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Typically developing before four years of age, LGS is associated with developmental delays.
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Use this medication only on the skin.
Preliminary research in animals suggests that triamterene may inhibit the urinary excretion of magnesium.
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If you have any of these health problems: High potassium levels or kidney disease.
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This list is not complete and other drugs may interact with hydrochlorothiazide and triamterene.
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Caution is advised in administering nonsteroidal anti-inflammatory agents with Triamterene and Hydrochlorothiazide Capsules, USP.
Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women.
In addition to its blood pressure-reducing effects, increased potassium intake may have independent vascular protective properties.
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Hypokalemia may occur in metabolic alkalosis, chronic diarrhea, Cushing syndrome, primary aldosteronism, and excessive use of deoxycorticosterone, cortisone, or ACTH.
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All patients changed from less bioavailable formulations to triamterene and hydrochlorothiazide should be monitored clinically and for serum potassium after the transfer.
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Promotes increased diuresis in patients resistant or only partially responsive to thiazides or other diuretics because of secondary hyperaldosteronism.
Hydrochlorothiazide, while effective, often causes low potassium levels in the blood.
This medicine may make your more sensitive to sunlight.
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The relation between the arrival of a diuretic at its site of action (determined on the basis of the rate of urinary excretion) and the natriuretic response determines the pharmacodynamics of the drug ( Figure 1 Pharmacodynamics of a Loop Diuretic.
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Tell your doctor right away if you have any unusual bleeding, such as nosebleeds, or bruising under your skin.
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You should not use the information contained here for diagnosing or treating a health problem or disease.
MRI should not be ordered in emergency situations because CT scanning is faster than MRI and has the advantages listed above.
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Drug excretion via the kidneys declines with age, the elderly should therefore be treated as renally insufficient patients.
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As the patient improves, a doctor will progressively recommend more activity.